His throat was dry. "There's nothing to it", White House spokesman Raj Shah told the Los Angeles Times.
Shah, pressed on the health concerns, dismissed suggestions the slurring signaled a deeper problem.
Noah wondered how Trump would feel if people began tweeting with the hashtag #DentureDonald.
"As moving as it was today to watch Donald Trump add fuel to the Middle East conflict", host Trevor Noah said on "The Daily Show" Wednesday night, "it was even more disturbing to watch the conflict between Donald Trump's teeth and his tongue".
A clip from the president's speech on Jerusalem appeared to show him struggling to enunciate certain words and sucking in his teeth-in a move that did not go unnoticed by the Twittersphere.
Trump's announcement that the USA will move its embassy from Tel Aviv to Jerusalem has raised concerns that the decision will spark violence and heighten tensions in the Middle East and put an end to hopes of a lasting peace because Jerusalem is disputed territory also claimed by Palestinians. But the pronunciation of those words appeared to slur. He sounded like he just had a drink with Bill Cosby. Because we all know that Democrats don't wear dentures, right?
"Because he's vain as hell", Noah said. He said there's no shame in having dentures, but, "there is shame in Donald Trump having dentures".
Stephen Colbert also joked about the president's speech.
"I am really looking forward to this January 30". And in fact, it doesn't matter that Trump has already made health an issue. "I'm just saying, 'Can you imagine?'"