And with United having survived a late scare to edge past Celta Vigo 2-1 on aggregate in their Europa League semi-final, European glory is within reach.
United know they can not break into the top four on the strength of their final two Premier League games against Southampton and Crystal Palace, as they trail Liverpool by eight points with only six left up for grabs.
Mourinho rejected the argument that United could lose momentum by fielding weakened teams in their last Premier League games. So if we can win a third title, or as you like to say, a second title, if we can do that it would be magnificent for us. So it's difficult, difficult, but we know what we are doing.
"The thinking is we have other good players, we have people that need and deserve to play and people that need and deserve to rest", Mourinho said to Sky Sports.
"Hopefully Crystal Palace don't have a lot to play for in the last game of the season, because I will make a lot of changes".
United are now sixth in the league table on 65 points, seven points adrift of fourth-placed team Manchester City.
And Red Devils boss Mourinho says Pogba will not be back in time for Wednesday's trip to St Mary's Stadium as he will be attending the funeral.
It's understood Carrick has told people close to him that he is ready to hang up his playing boots if United do finally call time on his 11-year stint in Manchester. I think Mourinho always fancies himself in a one-game shoot-out.
"We go to Stockholm to win the Europa League because it's a great opportunity for us to play Champions League next season". "And if he doesn't play the final, he has to play the remaining matches in the Premier League and give some rest to the others".
Mourinho then suggested that his position, stuck in sixth, but competing in finals, was more enviable than it looked.
He said: "We don't worry about pressure and opponents".
Mata added: "I think it's fair to congratulate Chelsea for winning the Premier League".
Mourinho insisted he thought the performance of individuals was "fine", but was not impressed with defending for both Spurs goals.