The report alleged that the Central Intelligence Agency, in conjunction with South Korea and a North Korean citizen identified only as Kim, attempted to kill the nation's leader at a recent military parade.
It's all caused North Korea's state-run Korean Central News Agency to label U.S. President Donald Trump as a "warmonger" and threaten a nuclear war.
North Korea accused the United States and South Korean intelligence agencies Friday of plotting to kill the nation's leader, Kim Jong Un, using "biochemical substances".
NKNews.org reports that the intelligence agencies are accused of attempting to carry out a biochemical attack against the leader during North Korea's April 15 military parade, which celebrated the 105th birthday of DPRK founding leader Kim Il Sung.
The U.S. has sent a warship to the region and installed a controversial anti-missile defence system in South Korea.
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North Korea vowed to "mercilessly destroy" the terrorists, the BBC reported Friday morning.
Dialogue between the North and the U.S. has in the past dampened potential conflict, as happened with trips to Pyongyang by former presidents Jimmy Carter in 1994 and Bill Clinton in 2009 and secretary of state Madeleine Albright in 2000.
President Trump has warned of "major, major conflict" with North Korea. When 13 North Korea restaurant workers in China defected to the South a year ago, Pyongyang claimed that South Korean spies kidnapped the workers.
"The duty of the two defense detachments are very important", the North Korean leader said while giving instructions for "rounding off" the combat preparation.
The news agency quoted a statement from the North's Ministry of State Security, saying "the last-ditch effort" of U.S. "imperialists" and the South had gone "beyond the limits". North Korea denied involvement.
Analysts said the accusations could be a pre-emptive attempt to try to dissuade Washington from any attempt at a surgical strike on its leadership, as suggested by some commentators.
But the allegation was also "aimed at keeping its people on their toes and strengthening its grip on them", and intended "to distance itself from the assassination of Jong-Nam who was killed by a chemical weapon".
South Korean Marine commander Lt. Gen. Jun Jin-goo also inspected units on Yeonpyeong Thursday, telling them to "be prepared and positioned well enough to fight enemy provocations at any time", a statement said.